Henrik Enghusen Poulsen took his medical diploma in 1976, and 10 years later he became dr. med. at the University of Copenhagen. From 1996 he has been professor of the Laboratory of Clinical Pharmacology in Copenhagen. He regularly presents at national and international meetings, and has conducted numerous research studies.
Clinical pharmacology is the science of therapeutics. The full potential of clinical pharmacology will be achieved only by research.
Advances made over the past decade, a description of diseases in molecular terms, improves the ways in which human diseases are detected, classified, monitored, and treated. Diseases such as heart disease, diabetes, and cancer.
In the laboratory we study biomarkers, pharmacokinetics, drug metabolism and genetics.
The overall aim of my study is to identify an intervention that reduces oxidative stress measured by 8-oxoGuo in patients with for instance type 2 diabetes.
The past decade has provided exciting insights into the role of oxidative stress in the development of for all degenerative deseases.
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Urinary excretion of the RNA oxidation marker 8-oxoGuo measured shortly after diagnosis of type 2 diabetes predicts long-term mortality independently of conventional risk factors. This finding suggests that 8-oxoGuo could serve as a new clinical biomarker in diabetes.
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